Lioresal: The Anti-spastic Formula
December 2nd, 2008

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Multiple sclerosis is the disease with the most spastic symptoms known so far. Medication such as Lioresal alleviates muscular tension and spasms, which are often accompanied by pain and rigidity.

How does Lioresal Work?

The main known action of Lioresal consists of the inhibition of reflexes at the level of the spinal cord. The drug is similar in structure to some neurotransmitter inhibitors. One of the main advantages of the drug appears to be connected with the high rate of absorption and quick elimination from the system. The drug actually remains unmodified during the passage through the body and it is excreted through the kidneys.

It is not uncommon to prescribe Lioresal to patients who suffer from spinal cord injuries or other health problems related to the spinal cord, as clear improvement has been reported. Nevertheless, Lioresal doesn't treat any kind of muscular spasms. One such case is that of skeletal muscle affections resulting from rheumatoid disorders. The same rule applies to the tremors associated with Parkinson's disease, for which Lirosal is ineffective.

Special Lioresal information

It is not recommended to interrupt Lioresal administration suddenly, since you may have to face serious withdrawal symptoms that include hallucinations and seizures.

Lioresal is a drug that depends on the proper functioning of the kidneys for elimination; if you suffer from any kidney problems you may not be allowed to use it. Close monitoring of the condition is necessary since Lioresal may lead to kidney impairment in the long run.

Patients whose medical records include some stroke history are less tolerant to Lioresal; hence administration should be done under strict medical observation.

What are the possible adverse reactions to Lioresal?

* The most common side effect reported so far has been drowsiness, which is usually manifest in 65% of the patients who use Lioresal.
* Though rarer, there have still been some cases of insomnia, depression, muscular pain, tremor and even epileptic seizures.
* For people with slight heart problems, Lioresal is likely to cause palpitations, chest pains or hypotension.
* In terms of digestive side effects, Lioresal may cause constipation and nausea, as well as abdominal pain and vomiting. However, such symptoms are pretty rare and mild in intensity. Contact the doctor right away if your condition deteriorates.
* Among some other less frequent side effects associated with Lioresal we could also mention pruritus, rashes, ankle edema, weight gain and excessive perspiration.

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