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The main use of Sporanox is to treat serious infections caused by fungi (such as histoplasmosis, aspergillosis and blast mycosis). Its capsules contain an active ingredient named itraconazole which is a type of medicine called a triazole antifungal.

Sporanox Information:

This medication prevents fungi from producing ergosterol - a very important component of fungal cell membranes. Because it is a part of the cell membrane, the absence of ergosterol weakens and damages the membrane and as a result, essentially causes the fungal cells to leak out, annihilating the fungi and clearing up the infection.

How do the most common fungal infections develop?

* Histoplasmosis - affects the blood, heart and lungs
* Blastomycosis - can affect the skin, lungs and bones
* Aspergillosis - attacks the kidneys, lungs and other organs

Sporanox can also be prescribed for onychomycosis - which infects the fingernails and toenails and it is also recommended for people with weak immune systems, such AIDS patients.

This active agent from Sporanox is over 99% bound and has no penetration into cerebrospinal fluid so it should not be used to treat any central nervous system infections.

Sporanox oral solution can cure the fungal infections (candidiasis) of the throat, mouth and esophagus and it is efficient for those with a weakened immunity or fever.

Every patient must make sure to take Sporanox exactly as prescribed. The oral solution shouldn't be taken with food but the capsules are much better absorbed after a full meal. The treatment must last at least 3 months to cure the infections completely.

People with allergy to other azoles antifungal medicines, cardiac problems, liver or kidney diseases or any nerve disorders should avoid Sporanox and also the drug is not recommended if you are pregnant or nursing a baby.

Everyone reacts in different ways after taking certain drugs and so Sporanox can also affect your organism in some situations. Their side effects are:

- hepatitis (inflammation of the liver)
- hail loss (alopecia)
- pulmonary edema (fluid on the lungs)
- dizziness, headache
- liver or heart failure
- menstrual disorders
- nausea, vomiting, abdominal plain, indigestion
- yellow skin (jaundice), yellow eyes
- dark urine
- unusual fatigue
- loss of appetite (anorexia)
- disorder of the peripheral nerves that can cause numbness (peripheral neurophaty)

Patients who must take Sporanox with other drugs metabolized by CYP3A4 should be closely monitored because the plasma concentration of these drugs increases.

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