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Drugs Information

Chloromycetine represents a type of antibiotic. This means that is used as part of the treatment of the infections that are caused by bacteria. Its active agent is named chloramphenicol. In the United States, it may also be found under its generic name. It is available in several dosage forms: eye drops, capsules, oral suspension, injection and ointment.

Important Facts

People are recommended to follow a treatment based on Chloromycetine only if the other drugs fail to be effective. This measure is taken because the side-effects that may appear after using this drug are very serious. They range from blood clotting problems to eye problems. The most severe side effect is represented by bone marrow depression. The blood problems that are associated to the Chloromycetine are hypoplastic anemia, blood dyscrasias, thrombocytopenia and granulocytopenia. A certain type of marrow depression that cannot be treated leads to aplastic anemia, a health condition that is fatal in the majority of the cases. Some forms of aplastic anemia end in leukemia. The less severe side-effects of Chloromycetine include nausea, vomiting, diarrhea and enterocolitis. However, these side-effects occur seldom. Headache, depression, delirium, optic and peripheral neuritis are also found among the adverse effects of this medication. Furthermore, some of the patients experience hypersensitivity reactions such as fever, skin irritation, urticaria and anaphylaxis.

Dosage and Administration of Chloromycetine

The dosage depends on the age of the patient as the adults require a certain amount in order to see any improvement of the symptoms, while the children need a smaller dose. The usual dosage for the adults is of 50 mg/kg daily. The amount must be split into 4 equal doses and taken each 6 hours. If the infection proves to be very severe, the dosage may be increased to 100 mg/kg daily. If the patient has liver or kidney problems, the drug cannot be eliminated from the body so easily. In this situation, the dosage must be modified so that it matches the capacity of the patient to metabolize the drug. The same dosage may be taken by children, too. Newborns, however, require a smaller dosage of 25 mg/kg daily. Each dose must be given at every 6 hours. When the newborns are two weeks old, they may be given a normal dose. If the newborns are discovered to have immature metabolic processes, then the concentration of the medicine in the blood must be accompanied by micro techniques.