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Cytoxan, also known as Cyclophosphamide, is a drug used to treat various kinds of cancers. It performs its primary function after synthesizing itself within the liver into two chemicals called phosphoramide and Acrolein.

These two chemicals are compounds which slow the growth of cancer cells by obstructing the availability of deoxyribonucleic acid also more commonly known as DNA. Another common name for cytoxan is cytotoxic.

Side effects

Although Cytoxan is very effective in reducing the progression of cancerous cells, it is also very dangerous as it affects the growth of other healthy cells. What is even more amazing is that this drug suppresses the immune system and is an immunosuppressive.

Used specifically to treat severe cancers like ovarian cancer, breast cancer, and leukemia, this medication is also approved for treating nephrotic syndrome in children. Nephrotic syndrome is the name of a disorder in which the kidneys leak excess protein into wastes thrown into the bladder in the form of urine. This disorder can become severe as large amounts of protein are removed leading to low levels of protein the blood.

Because of its medicinal uses, this drug has been used to treat many disorders and ailments including severe rheumatoid arthritis, lupus erythematosus, and Wegener's granulomatosis. However, it is generally not recommended by leading medical authorities for such a use. In other words, Cytoxan is a medically tested and recommended drug only for the treatment of cancer and nephrotic syndrome.

Dosage

According to medical research and tests, this drug should be taken in a specific dosage. The recommended dosage of this varies from 1-5 mg/kg daily. While oral dosage is 1-5mg/kg, when taken through injections, dosage levels are around 40-50 mg/kg. Dosage of any medicine is specifically tailored to the response of an individual's body towards the afflicting disease.

Cytoxan, in rare instances, has been linked to heart failure. The usual initial dose for adults and children is administered intravenously over 3-5 days in divided doses. The usual oral dose is 1-5 mg/kg daily. Subsequent maintenance doses are adjusted based on the response of the tumor to treatment and the patient's side effects. Apart from heart failure, excess use has been blamed for kidney failure as well. You should consult a doctor to make sure you take the minimally adequate amount of Cytoxan for the treatment of cancer and nephrotic syndrome.

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