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Adriamycin Cytoxan:what Is It?
January 9th, 2009

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Adriamycin Cytoxan is a combination of two chemotherapy drugs, Adriamycin and Cytoxan, for the adjuvant treatment of breast cancer. Individually, these are potent medications on their own but have an increased effectiveness when put into a combination. It has also become quite common to add the drug, Taxol, to the combination in hopes of further increasing the combinations effectiveness at preventing the recurrence of tumors. The adjuvant therapy has been effectively used after surgical procedures and removal of the original tumor to prevent or slow the progress of recurring tumor cells.

Does Adriamycin Cytoxan have any side effects?

Adriamycin Cytoxan therapy is intended to curb the reoccurrence of cancer by inhibiting the growth of the faster growing cancer cells and ridding the body of these cells. This process of therapy is not without side effects, however. The Adriamycin Cytoxan therapy also attacks the normal faster growing cells of the human body as well. This causes the typical hair loss and mouth sores associated with chemotherapy treatments. The treatment also effects the cells produced by the bone marrow, the white and red blood cells and platelets. While the Adriamycin Cytoxan therapy is scheduled over time to allow regeneration of healthy normal cells, the patient can still expect a decreased ability to stave off infection, a limited oxygen carrying capacity in the blood and a decrease in the blood clotting platelets, necessary to stop bleeding. For these reasons, patients who are using Adriamycin Cytoxan therapy will feel physically weakened and will suffer from lowered immune systems.

Adriamycin Cytoxan's individual components propose side effects of their own as we shall discuss. Adriamycin has the above listed side effects in addition to changes in the nails, discoloration of the urine and inability to withstand prolonged exposure to sunlight. Cytoxan has the additional effects of decreasing the appetite, changing the way tastes are perceived, nasal congestion, irritation of the bladder and changes to the menstrual cycle. To decrease the negative side effects of these drugs, it is recommended that the patient drinks plenty of water in the twenty four hour period following treatment, regular use of an alcohol free mouthwash and avoiding exposure to sunlight. It is also recommended that the patient use a sun block with an SPF level of at least 15 and protective clothing if exposure to sunlight cannot be avoided during Adriamycin Cytoxan therapy.

Should I stop taking Adriamycin Cytoxin because of the side effects?

Though these side effects may seem quite harsh, it is very important that the patient maintains the schedule of Adriamycin Cytoxan therapy. Virtually all of the side effects are temporary and their severity will differ by dosages and the individual patient. It is vital that the patient receives the full dosage at the scheduled times for the medications to be effective as an adjuvant treatment for cancer so being well informed as to side effect management and keeping a close connection to one's support group is vital. A patient receiving Adriamycin Cytoxan treatment should remain in steady contact with their health care provider to assist with support and management of side effects.









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